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Blood-Brain Barrier and Delivery of Protein and Gene Therapeutics to Brain

Alzheimer’s disease (AD) and treatment of the brain in aging require the development of new biologic drugs, such as recombinant proteins or gene therapies. Biologics are large molecule therapeutics that do not cross the blood-brain barrier (BBB). BBB drug delivery is the limiting factor in the futur...

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Dades bibliogràfiques
Publicat a:Front Aging Neurosci
Autor principal: Pardridge, William M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966240/
https://ncbi.nlm.nih.gov/pubmed/31998120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00373
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