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Blood-Brain Barrier and Delivery of Protein and Gene Therapeutics to Brain

Alzheimer’s disease (AD) and treatment of the brain in aging require the development of new biologic drugs, such as recombinant proteins or gene therapies. Biologics are large molecule therapeutics that do not cross the blood-brain barrier (BBB). BBB drug delivery is the limiting factor in the futur...

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Bibliografske podrobnosti
izdano v:Front Aging Neurosci
Glavni avtor: Pardridge, William M.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966240/
https://ncbi.nlm.nih.gov/pubmed/31998120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00373
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