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Potent, selective and cell penetrant inhibitors of SF-1 by functional uHTS

The Steroidogenic factor 1 (SF-1, also known as NR5A1) is a transcription factor belonging to the nuclear receptor superfamily. Whereas most of the members of this family have been extensively characterized, the therapeutic potential and pharmacology of SF-1 still remains elusive. Described here is...

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Detalhes bibliográficos
Main Authors: Madoux, Franck, Li, Xiaolin, Chase, Peter, Zastrow, Gina, Cameron, Michael D., Conkright, Juliana J., Griffin, Patrick R., Thacher, Scott, Hodder, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228235/
https://ncbi.nlm.nih.gov/pubmed/18334597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.045963
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