Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons

Neuronal migration is essential for the development of the mammalian brain. Here, we document severe defects in neuronal migration and reduced numbers of neurons in lamin B1–deficient mice. Lamin B1 deficiency resulted in striking abnormalities in the nuclear shape of cortical neurons; many neurons...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Coffinier, Catherine, Jung, Hea-Jin, Nobumori, Chika, Chang, Sandy, Tu, Yiping, Barnes, Richard H., Yoshinaga, Yuko, de Jong, Pieter J., Vergnes, Laurent, Reue, Karen, Fong, Loren G., Young, Stephen G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2011
Onderwerpen:
Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226484/
https://ncbi.nlm.nih.gov/pubmed/21976703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-06-0504
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items