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Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis

The mycobacterial biotin protein ligase (MtBPL) globally regulates lipid metabolism in Mtb through the posttranslational biotinylation of acyl coenzyme A carboxylases involved in lipid biosynthesis that catalyze the first step in fatty acid biosynthesis and pyruvate coenzyme A carboxylase, a glucone...

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Xehetasun bibliografikoak
Egile Nagusiak: Duckworth, Benjamin P., Geders, Todd W., Tiwari, Divya, Boshoff, Helena I., Sibbald, Paul A., Barry, Clifton E., Schnappinger, Dirk, Finzel, Barry C., Aldrich, Courtney C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225891/
https://ncbi.nlm.nih.gov/pubmed/22118677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.08.013
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