Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor

Receptor-regulated cellular signaling often is mediated by formation of transient, heterogeneous protein complexes of undefined structure. We used single and two-color photoactivated-localization microscopy (PALM) to study complexes downstream of the T cell antigen receptor (TCR) in single molecule...

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Main Authors: Sherman, Eilon, Barr, Valarie, Manley, Suliana, Patterson, George, Balagopalan, Lakshmi, Akpan, Itoro, Regan, Carole K., Merrill, Robert K., Sommers, Connie L., Lippincott-Schwartz, Jennifer, Samelson, Lawrence E.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225724/
https://ncbi.nlm.nih.gov/pubmed/22055681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.10.004
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