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The mTOR (Mammalian Target of Rapamycin) Kinase Maintains Integrity of mTOR Complex 2
In higher eukaryotes, growth factors promote anabolic processes and stimulate cell growth, proliferation, and survival by activation of the phosphoinositide 3-kinase (PI3K)/Akt pathway. Deregulation of PI3K/Akt signaling is linked to human diseases, including cancer and metabolic disorders. The PI3K...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220582/ https://ncbi.nlm.nih.gov/pubmed/21965657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.282590 |
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