Somatic structural rearrangements in genetically engineered mouse mammary tumors

BACKGROUND: Here we present the first paired-end sequencing of tumors from genetically engineered mouse models of cancer to determine how faithfully these models recapitulate the landscape of somatic rearrangements found in human tumors. These were models of Trp53-mutated breast cancer, Brca1- and B...

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Главные авторы: Varela, Ignacio, Klijn, Christiaan, Stephens, Phillip J, Mudie, Laura J, Stebbings, Lucy, Galappaththige, Danushka, van der Gulden, Hanneke, Schut, Eva, Klarenbeek, Sjoerd, Campbell, Peter J, Wessels, Lodewyk FA, Stratton, Michael R, Jonkers, Jos, Futreal, P Andrew, Adams, David J
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2010
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218656/
https://ncbi.nlm.nih.gov/pubmed/20942901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-10-r100
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