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Identification of Networks of Co-Occurring, Tumor-Related DNA Copy Number Changes Using a Genome-Wide Scoring Approach

Tumorigenesis is a multi-step process in which normal cells transform into malignant tumors following the accumulation of genetic mutations that enable them to evade the growth control checkpoints that would normally suppress their growth or result in apoptosis. It is therefore important to identify...

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Main Authors: Klijn, Christiaan, Bot, Jan, Adams, David J., Reinders, Marcel, Wessels, Lodewyk, Jonkers, Jos
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791203/
https://ncbi.nlm.nih.gov/pubmed/20052266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000631
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