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Chuvash polycythemia VHL(R200W) mutation is associated with down-regulation of hepcidin expression
Hypoxia is known to reduce the expression of hepcidin, the master regulator of iron metabolism. However, it is not clear whether this response is primarily related to increased erythropoiesis driven by hypoxically stimulated erythropoietin or to a more direct effect of hypoxia on hepcidin expression...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3217409/ https://ncbi.nlm.nih.gov/pubmed/21876117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-345512 |
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