Elevated homocysteine, glutathione and cysteinylglycine concentrations in patients homozygous for the Chuvash polycythemia VHL mutation

In Chuvash polycythemia, homozygous von Hippel-Lindau (VHL) 598C>T leads to increased hypoxia inducible factor-1α and 2α, thromboses and lower systemic blood pressures. Circulating homocysteine, glutathione, γ-glutamyltransferase and cysteinylglycine concentrations were higher in 34 VHL598C>T...

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Detalhes bibliográficos
Main Authors: Sergueeva, Adelina I., Miasnikova, Galina Y., Okhotin, Daniel J., Levina, Alla A., Debebe, Zufan, Ammosova, Tatiana, Niu, Xiaomei, Romanova, Elena A., Nekhai, Sergei, DiBello, Patricia M., Jacobsen, Donald W., Prchal, Josef T., Gordeuk, Victor R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852873/
https://ncbi.nlm.nih.gov/pubmed/18223282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.11851
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