Elevated homocysteine, glutathione and cysteinylglycine concentrations in patients homozygous for the Chuvash polycythemia VHL mutation

In Chuvash polycythemia, homozygous von Hippel-Lindau (VHL) 598C>T leads to increased hypoxia inducible factor-1α and 2α, thromboses and lower systemic blood pressures. Circulating homocysteine, glutathione, γ-glutamyltransferase and cysteinylglycine concentrations were higher in 34 VHL598C>T...

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Autors principals: Sergueeva, Adelina I., Miasnikova, Galina Y., Okhotin, Daniel J., Levina, Alla A., Debebe, Zufan, Ammosova, Tatiana, Niu, Xiaomei, Romanova, Elena A., Nekhai, Sergei, DiBello, Patricia M., Jacobsen, Donald W., Prchal, Josef T., Gordeuk, Victor R.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852873/
https://ncbi.nlm.nih.gov/pubmed/18223282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.11851
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