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Molecular and Cellular Evidence for the Alternative Lengthening of Telomeres (ALT) Mechanism in Chicken

Telomere maintenance is an important genetic mechanism controlling cellular proliferation. Normally, telomeres are maintained by telomerase which is downregulated upon cellular differentiation in most somatic cell lineages. Telomerase activity is upregulated in immortalized cells and cancers to supp...

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Detalhes bibliográficos
Main Authors: O'Hare, T.H., Delany, M.E.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214677/
https://ncbi.nlm.nih.gov/pubmed/21822009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000330125
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