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Alternative lengthening of telomeres: from molecular mechanisms to therapeutic outlooks
To escape replicative senescence, cancer cells have to overcome telomere attrition during DNA replication. Most of cancers rely on telomerase to extend and maintain telomeres, but 4–11% of cancers use a homologous recombination-based pathway called alternative lengthening of telomeres (ALT). ALT is...
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| Publicado no: | Cell Biosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7063710/ https://ncbi.nlm.nih.gov/pubmed/32175073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00391-6 |
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