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Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc
AIMS: Hyperhomocysteinaemia is an independent risk factor for atherosclerotic vascular disease and is associated with vascular endothelial dysfunction. Homocysteine modulates cellular methylation reactions. P66shc is a protein that promotes oxidative stress whose expression is governed by promoter m...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3211975/ https://ncbi.nlm.nih.gov/pubmed/21933910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr250 |
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