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CRIF1 Deficiency Induces p66shc-Mediated Oxidative Stress and Endothelial Activation
Mitochondrial dysfunction has been implicated in the pathophysiology of various cardiovascular diseases. CRIF1 is a protein present in the mitochondria associated with large mitoribosomal subunits, and CRIF1 knockdown induces mitochondrial dysfunction and promotes ROS production. p66shc is a redox e...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048193/ https://ncbi.nlm.nih.gov/pubmed/24906005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098670 |
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