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siRNA-Aptamer Chimeras on Nanoparticles, Preserving Targeting Functionality for Effective Gene Silencing
siRNA-aptamer chimera is emerging as a highly promising approach for cell-type specific delivery of siRNA due to the outstanding targeting capability of aptamer and the compatibility of chimera with native ribonuclease (Dicer) processing. For efficient RNA interference (RNAi), however, additional ch...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210423/ https://ncbi.nlm.nih.gov/pubmed/21936502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn202772p |
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