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siRNA-Aptamer Chimeras on Nanoparticles, Preserving Targeting Functionality for Effective Gene Silencing

siRNA-aptamer chimera is emerging as a highly promising approach for cell-type specific delivery of siRNA due to the outstanding targeting capability of aptamer and the compatibility of chimera with native ribonuclease (Dicer) processing. For efficient RNA interference (RNAi), however, additional ch...

詳細記述

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書誌詳細
主要な著者: Bagalkot, Vaishali, Gao, Xiaohu
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210423/
https://ncbi.nlm.nih.gov/pubmed/21936502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn202772p
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