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siRNA-Aptamer Chimeras on Nanoparticles, Preserving Targeting Functionality for Effective Gene Silencing

siRNA-aptamer chimera is emerging as a highly promising approach for cell-type specific delivery of siRNA due to the outstanding targeting capability of aptamer and the compatibility of chimera with native ribonuclease (Dicer) processing. For efficient RNA interference (RNAi), however, additional ch...

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Detalhes bibliográficos
Main Authors: Bagalkot, Vaishali, Gao, Xiaohu
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210423/
https://ncbi.nlm.nih.gov/pubmed/21936502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn202772p
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