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Aptamer-siRNA Chimeras: Discovery, Progress, and Future Prospects

Synthetic nucleic acid ligands (aptamers) have emerged as effective delivery tools for many therapeutic oligonucleotide-based drugs, including small interfering RNAs (siRNAs). In this review, we summarize recent progress in the aptamer selection technology that has made possible the identification o...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Kruspe, Sven, Giangrande, Paloma H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618303/
https://ncbi.nlm.nih.gov/pubmed/28792479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines5030045
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