Загрузка...

ULK1 inhibits the kinase activity of mTORC1 and cell proliferation

ULK1 (Unc51-like kinase, hATG1) is a Ser/Thr kinase that plays a key role in inducing autophagy in response to starvation. ULK1 is phosphorylated and negatively regulated by the mammalian target of rapamycin complex 1 (mTORC1). Previous studies have shown that ULK1 is not only a downstream effector...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Jung, Chang Hwa, Seo, Minchul, Otto, Neil Michael, Kim, Do-Hyung
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210307/
https://ncbi.nlm.nih.gov/pubmed/21795849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.10.16660
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!