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Transgenerational Epigenetic Instability Is a Source of Novel Methylation Variants

Epigenetic information, which may affect an organisms’ phenotype, can be stored and stably inherited in the form of cytosine DNA methylation. Changes in DNA methylation can produce meiotically stable epialleles that affect transcription and morphology, but the rates of spontaneous gain or loss of DN...

詳細記述

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書誌詳細
主要な著者: Schmitz, Robert J., Schultz, Matthew D., Lewsey, Mathew G., O’Malley, Ronan C., Urich, Mark A., Libiger, Ondrej, Schork, Nicholas J., Ecker, Joseph R.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210014/
https://ncbi.nlm.nih.gov/pubmed/21921155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1212959
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