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Simulation-based homozygosity mapping with the GAW14 COGA dataset on alcoholism

BACKGROUND: We have developed a simulation-based approach to the analysis of shared homozygous chromosomal segments and have applied it to data on allele sharing among alcoholics in a single Collaborative Study on the Genetics of Alcoholism pedigree. Our assessment of sharing involved the use of a s...

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Autori principali: Libiger, Ondrej, Schork, Nicholas J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866750/
https://ncbi.nlm.nih.gov/pubmed/16451645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S35
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