تحميل...

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration Resistant Prostate Cancer and is Upregulated by Treatment with CYP17A1 Inhibitors

Relapse of castration-resistant prostate cancer (CRPC) that occurs after androgen deprivation therapy of primary prostate cancer can be mediated by reactivation of the androgen receptor (AR). One important mechanism mediating this AR reactivation is intratumoral conversion of the weak adrenal androg...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Cai, Changmeng, Chen, Sen, Ng, Patrick, Bubley, Glenn J., Nelson, Peter S., Mostaghel, Elahe A., Marck, Brett, Matsumoto, Alvin M., Simon, Nicholas I., Wang, Hongyun, Chen, Shaoyong, Balk, Steven P.
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	2011
الموضوعات:	Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3209585/ https://ncbi.nlm.nih.gov/pubmed/21868758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0532
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration Resistant Prostate Cancer and is Upregulated by Treatment with CYP17A1 Inhibitors

مواد مشابهة