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ClpXP, an ATP-powered unfolding and protein-degradation machine
ClpXP is a AAA+ protease that uses the energy of ATP binding and hydrolysis to perform mechanical work during targeted protein degradation within cells. ClpXP consists of hexamers of a AAA+ ATPase (ClpX) and a tetradecameric peptidase (ClpP). Asymmetric ClpX hexamers bind unstructured peptide tags i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209554/ https://ncbi.nlm.nih.gov/pubmed/21736903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.06.007 |
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