Chargement en cours...
Largazole and Analogues with Modified Metal-Binding Motifs Targeting Histone Deacetylases: Synthesis and Biological Evaluation
The histone deacetylase inhibitor, largazole 1 was synthesized by a convergent approach which involved several efficient and high yielding single pot multistep protocols. Initial attempts using t-butyl as thiol protecting group proved problematic and synthesis was accomplished by switching to trityl...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208063/ https://ncbi.nlm.nih.gov/pubmed/21936551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200432a |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|