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Differential regulation of self-reactivity discriminates between IgG(+) human circulating memory B cells and bone marrow plasma cells
Long-term humoral immunity is maintained by the formation of high-affinity class-switched memory B cells and long-lived antibody-secreting plasma cells. In healthy humans, a substantial fraction of IgG-positive memory B cells express self-reactive and polyreactive IgG antibodies that frequently deve...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207704/ https://ncbi.nlm.nih.gov/pubmed/22025722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113395108 |
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