Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors

Persistent autoantibody production in patients with systemic lupus erythematosus (SLE) suggests the existence of autoreactive humoral memory, but the frequency of self-reactive memory B cells in SLE has not been determined. Here, we report on the reactivity of 200 monoclonal antibodies from single I...

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Detaylı Bibliyografya
Asıl Yazarlar: Mietzner, Brun, Tsuiji, Makoto, Scheid, Johannes, Velinzon, Klara, Tiller, Thomas, Abraham, Klaus, Gonzalez, Jose B., Pascual, Virginia, Stichweh, Dorothee, Wardemann, Hedda, Nussenzweig, Michel C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474524/
https://ncbi.nlm.nih.gov/pubmed/18621685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803644105
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