Chargement en cours...
A checkpoint for autoreactivity in human IgM(+) memory B cell development
Autoantibodies are removed from the repertoire at two checkpoints during B cell development in the bone marrow and the periphery. Despite these checkpoints, up to 20% of the antibodies expressed by mature naive B cells in healthy humans show low levels of self-reactivity. To determine whether self-r...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2006
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118214/ https://ncbi.nlm.nih.gov/pubmed/16446381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052033 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|