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Autoreactivity in human IgG+ memory B cells
More than half of the nascent B cells in humans initially express autoreactive antibodies. However, most of these autoantibodies are removed from the repertoire at two checkpoints before maturation into naïve B cells. A third checkpoint excludes remaining autoantibodies from the antigen-experienced...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1839941/ https://ncbi.nlm.nih.gov/pubmed/17306569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.01.009 |
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