Anti-angiogenic and anti-metastatic activity of JAK inhibitor AZD1480

STAT3 has important functions in both tumor cells and the tumor microenvironment to facilitate cancer progression. The STAT regulatory kinase JAK has been strongly implicated in promoting oncogenesis of various solid tumors, including through the use of JAK kinase inhibitors such as AZD1480. However...

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Bibliografski detalji
Glavni autori: Xin, Hong, Herrmann, Andreas, Reckamp, Karen, Zhang, Wang, Pal, Sumanta, Hedvat, Michael, Zhang, Chunyan, Liang, Wei, Scuto, Anna, Weng, Shaobu, Morosini, Deborah, Cao, Zhu A., Zinda, Michael, Figlin, Robert, Huszar, Dennis, Jove, Richard, Yu, Hua
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206173/
https://ncbi.nlm.nih.gov/pubmed/21920898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1217
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