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The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma

Aberrant activation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway has been reported to promote proliferation and survival of Hodgkin and Reed–Sternberg cells of Hodgkin lymphoma (HL). We investigated the activity of the JAK inhibitor AZD1480 in HL-derived...

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Bibliografske podrobnosti
Main Authors: Derenzini, E, Lemoine, M, Buglio, D, Katayama, H, Ji, Y, Davis, R E, Sen, S, Younes, A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255510/
https://ncbi.nlm.nih.gov/pubmed/22829094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.46
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