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JAK1/2 Inhibitors AZD1480 and CYT387 Inhibit Canine B‐Cell Lymphoma Growth by Increasing Apoptosis and Disrupting Cell Proliferation

BACKGROUND: Canine diffuse large B‐cell lymphoma (DLBCL) is a common and aggressive hematologic malignancy. The lack of conventional therapies with sustainable efficacy warrants further investigation of novel therapeutics. The Janus kinase (JAK) and signal transducer and activator of transcription (...

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Bibliographische Detailangaben
Veröffentlicht in:J Vet Intern Med
Hauptverfasser: Lu, Z., Hong, C.C., Jark, P.C., Assumpção, A.L.F.V., Bollig, N., Kong, G., Pan, X.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697192/
https://ncbi.nlm.nih.gov/pubmed/28960447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.14837
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