JAK1/2 Inhibitors AZD1480 and CYT387 Inhibit Canine B‐Cell Lymphoma Growth by Increasing Apoptosis and Disrupting Cell Proliferation

BACKGROUND: Canine diffuse large B‐cell lymphoma (DLBCL) is a common and aggressive hematologic malignancy. The lack of conventional therapies with sustainable efficacy warrants further investigation of novel therapeutics. The Janus kinase (JAK) and signal transducer and activator of transcription (...

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Publicado no:J Vet Intern Med
Main Authors: Lu, Z., Hong, C.C., Jark, P.C., Assumpção, A.L.F.V., Bollig, N., Kong, G., Pan, X.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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SMALL ANIMAL
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697192/
https://ncbi.nlm.nih.gov/pubmed/28960447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.14837
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