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Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity
Cellular senescence acts as a potent barrier to tumorigenesis and contributes to the anti-tumor activity of certain chemotherapeutic agents. Senescent cells undergo a stable cell cycle arrest controlled by RB and p53 and, in addition, display a senescence-associated secretory phenotype (SASP) involv...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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Cold Spring Harbor Laboratory Press
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205583/ https://ncbi.nlm.nih.gov/pubmed/21979375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.17276711 |
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