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The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence
Oncogene-induced senescence is an anti-proliferative stress response program that acts as a fail-safe mechanism to limit oncogenic transformation and is regulated by the retinoblastoma protein (RB) and p53 tumor suppressor pathways. We identify the atypical E2F family member E2F7 as the only E2F tra...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404383/ https://ncbi.nlm.nih.gov/pubmed/22802529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.196238.112 |
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