Sprouty1 induces a senescence-associated secretory phenotype by regulating NFκB activity: implications for tumorigenesis

Genes of the Sprouty family (Spry1–4) are feedback inhibitors of receptor tyrosine kinase (RTK) signaling. As such, they restrain proliferation of many cell types and have been proposed as tumor-suppressor genes. Although their most widely accepted target is the Extracellular-regulated kinases (ERK)...

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Detaylı Bibliyografya
Asıl Yazarlar: Macià, A, Vaquero, M, Gou-Fàbregas, M, Castelblanco, E, Valdivielso, J M, Anerillas, C, Mauricio, D, Matias-Guiu, X, Ribera, J, Encinas, M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890957/
https://ncbi.nlm.nih.gov/pubmed/24270409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.161
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