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Direct observation of disulfide isomerization in a single protein
Photochemical uncaging techniques use light to release active molecules from otherwise inert compounds. Here we expand this class of techniques by demonstrating the mechanical uncaging of a reactive species within a single protein. We prove this novel technique by capturing the regiospecific reactio...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205468/ https://ncbi.nlm.nih.gov/pubmed/22024885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1155 |
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