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Direct observation of disulfide isomerization in a single protein

Photochemical uncaging techniques use light to release active molecules from otherwise inert compounds. Here we expand this class of techniques by demonstrating the mechanical uncaging of a reactive species within a single protein. We prove this novel technique by capturing the regiospecific reactio...

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Detalhes bibliográficos
Main Authors: Alegre-Cebollada, Jorge, Kosuri, Pallav, Rivas-Pardo, Jaime Andrés, Fernández, Julio M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205468/
https://ncbi.nlm.nih.gov/pubmed/22024885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1155
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