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Single-molecule Force Spectroscopy Approach to Enzyme Catalysis

Enzyme catalysis has been traditionally studied using a diverse set of techniques such as bulk biochemistry, x-ray crystallography, and NMR. Recently, single-molecule force spectroscopy by atomic force microscopy has been used as a new tool to study the catalytic properties of an enzyme. In this app...

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Bibliographic Details
Main Authors: Alegre-Cebollada, Jorge, Perez-Jimenez, Raul, Kosuri, Pallav, Fernandez, Julio M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885171/
https://ncbi.nlm.nih.gov/pubmed/20382731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.011932
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