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Protein folding drives disulfide formation

PDI catalyzes the oxidative folding of disulfide-containing proteins. However, the sequence of reactions leading to a natively folded and oxidized protein remains unknown. Here we demonstrate a technique that enables independent measurements of disulfide formation and protein folding. We find that n...

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Detalhes bibliográficos
Main Authors: Kosuri, Pallav, Alegre-Cebollada, Jorge, Feng, Jason, Kaplan, Anna, Inglés-Prieto, Álvaro, Badilla, Carmen L., Stockwell, Brent R., Sánchez-Ruiz, José M., Holmgren, Arne, Fernández, Julio M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506382/
https://ncbi.nlm.nih.gov/pubmed/23141538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.036
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