Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia

T-cell large granular lymphocyte leukemia (T-LGLL) is characterized by chronic lymphoproliferation of cytotoxic T lymphocytes (CTLs) and is associated with lineage-restricted cytopenias. Introduction of T-cell receptor (TCR) variable β-chain (Vβ) monoclonal antibodies has facilitated identification...

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Détails bibliographiques
Auteurs principaux: Clemente, Michael J., Wlodarski, Marcin W., Makishima, Hideki, Viny, Aaron D., Bretschneider, Isabell, Shaik, Mohammad, Bejanyan, Nelli, Lichtin, Alan E., His, Eric D., Paquette, Ronald L., Loughran, Thomas P., Maciejewski, Jaroslaw P.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Immunobiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204910/
https://ncbi.nlm.nih.gov/pubmed/21865345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-338517
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