Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8(+) large granular lymphocyte leukemia

BACKGROUND: T-cell large granular lymphocytic leukemia is a clonal proliferation of cytotoxic T-lymphocytes which often results in severe cytopenia. Current treatment options favor chronic immunosuppression. Alemtuzumab, a humanized monoclonal antibody against glycophosphatidylinositol-anchored CD52...

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Detalhes bibliográficos
Main Authors: Mohan, Sanjay R., Clemente, Michael J., Afable, Manuel, Cazzolli, Heather N., Bejanyan, Nelli, Wlodarski, Marcin W., Lichtin, Alan E., Maciejewski, Jaroslaw P.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754957/
https://ncbi.nlm.nih.gov/pubmed/19794084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.009191
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