Molecular strategies for detection and quantitation of clonal cytotoxic T-cell responses in aplastic anemia and myelodysplastic syndrome

Immune mechanisms are involved in the pathophysiology of aplastic anemia (AA) and myelodysplastic syndrome (MDS). Immune inhibition can result from cytotoxic T cell (CTL) attack against normal hematopoiesis or reflect immune surveillance. We used clonally unique T-cell receptor (TCR) variable β-chai...

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Hauptverfasser: Wlodarski, Marcin W., Gondek, Lukasz P., Nearman, Zachary P., Plasilova, Magdalena, Kalaycio, Matt, Hsi, Eric D., Maciejewski, Jaroslaw P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: © 2006 by The American Society of Hematology 2006
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895579/
https://ncbi.nlm.nih.gov/pubmed/16614248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3902
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