Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice

Type 1 diabetes (T1D) is an autoimmune disease that shows familial aggregation in humans and likely has genetic determinants. Disease linkage studies have revealed many susceptibility loci for T1D in mice and humans. The mouse T1D susceptibility locus insulin-dependent diabetes susceptibility 3 (Idd...

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Bibliografische gegevens
Hoofdauteurs: Liu, Sue M., Lee, David H., Sullivan, Jenna M., Chung, Denise, Jäger, Anneli, Shum, Bennett O.V., Sarvetnick, Nora E., Anderson, Ana C., Kuchroo, Vijay K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204832/
https://ncbi.nlm.nih.gov/pubmed/22019586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46187
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