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The Incidence of Type-1 Diabetes in NOD Mice Is Modulated by Restricted Flora Not Germ-Free Conditions

In the NOD mouse, the incidence of type-1 diabetes is thought to be influenced by the degree of cleanliness of the mouse colony. Studies collectively demonstrate that exposure to bacterial antigen or infection in the neonatal period prevents diabetes [1], [2], [3], [4], [5], [6], [7], [8], [9], [10]...

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Autores principales: King, Cecile, Sarvetnick, Nora
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045412/
https://ncbi.nlm.nih.gov/pubmed/21364875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017049
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