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Normal Incidence of Diabetes in NOD Mice Tolerant to Glutamic Acid Decarboxylase

Experiments in nonobese diabetic (NOD) mice that lacked expression of glutamic acid decarboxylase (GAD) in β cells have suggested that GAD represents an autoantigen essential for initiating and maintaining the diabetogenic immune response. Several attempts of inducing GAD-specific recessive toleranc...

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Détails bibliographiques
Auteurs principaux: Jaeckel, Elmar, Klein, Ludger, Martin-Orozco, Natalia, von Boehmer, Harald
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193961/
https://ncbi.nlm.nih.gov/pubmed/12796471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030215
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