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Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice

Recent evidence has highlighted the role of histamine in inflammation. Since this monoamine has also been strongly implicated in the pathogenesis of type-1 diabetes, we assessed its effect in the nonobese diabetic (NOD) mouse model. To this end, we used mice (inactivated) knocked out for the gene en...

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Autors principals: Manal Alkan, François Machavoine, Rachel Rignault, Julie Dam, Michel Dy, Nathalie Thieblemont
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2015-01-01
Col·lecció:Journal of Diabetes Research
Accés en línia:http://dx.doi.org/10.1155/2015/965056
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