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Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice

Recent evidence has highlighted the role of histamine in inflammation. Since this monoamine has also been strongly implicated in the pathogenesis of type-1 diabetes, we assessed its effect in the nonobese diabetic (NOD) mouse model. To this end, we used mice (inactivated) knocked out for the gene en...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Alkan, Manal, Machavoine, François, Rignault, Rachel, Dam, Julie, Dy, Michel, Thieblemont, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452174/
https://ncbi.nlm.nih.gov/pubmed/26090474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/965056
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