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NOD mice deficient in chromogranin A are protected from autoimmune diabetes

T cells reactive to β-cell antigens are critical players in the development of autoimmune type 1 diabetes (T1D). Using a panel of diabetogenic CD4 T cell clones derived from the non-obese diabetic (NOD) mouse, we recently identified the β-cell secretory granule protein, chromogranin A (ChgA), as a n...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Baker, Rocky L, Bradley, Brenda, Wiles, Timothy A, Lindsay, Robin S, Barbour, Gene, Delong, Thomas, Friedman, Rachel S, Haskins, Kathryn
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684982/
https://ncbi.nlm.nih.gov/pubmed/26608914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501190
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