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Diabetogenic T-Cell Clones Recognize an Altered Peptide of Chromogranin A
Chromogranin A (ChgA) has been identified as the antigen target for three NOD-derived, diabetogenic CD4 T-cell clones, including the well-known BDC-2.5. These T-cell clones respond weakly to the peptide WE14, a naturally occurring proteolytic cleavage product from ChgA. We show here that WE14 can be...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501882/ https://ncbi.nlm.nih.gov/pubmed/22912420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0112 |
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